Angelo – do you have a specific song in mind? What’s “very short”?
Obviously you could look at different voicing for a verse or two. Or, if your skill level allows, improvising a new melody line. Most popular songs are short – 32 bars, AABA, and the A sections are usually pretty similar harmonically. So trying to create a 10-minute solo piano version of “Misty” is difficult for many people (and their audiences).
That being said, there’s nothing to stop you from experimenting with tempo, voicing, melody, and musical “attitude” to see what you can create from that short song form.